Publications since 2019


Lehmann J, Thiele S, Baschant U, Rachner TD, Niehrs C, Hofbauer LC and Rauner M (2021) Mice lacking DKK1 in T cells exhibit high bone mass and are protected from estrogen-deficiency-induced bone loss. iScience, doi: 10.1016/j.isci.2021.102224 Link


Lee H, Seidl C, Sun R, Glinka A and Niehrs C (2020) R-spondins are BMP receptor antagonists in Xenopus early embryonic development. Nat Commun, doi: 10.1038/s41467-020-19373-w Link

Harshuk-Shabso S, Dressler H, Niehrs C, Aamar E and Enshell-Seijffers D (2020) Fgf and Wnt signaling interaction in the mesenchymal niche regulates the murine hair cycle clock. Nat Commun, doi: 10.1038/s41467-020-18643-x Link

Leismann J, Spagnuolo M, Pradhan M, Wacheul L, Vu MA, Musheev M, Mier P, Andrade‐Navarro MA, Graille M, Niehrs C, Lafontaine DL and Roignant J (2020) The 18S ribosomal RNA m 6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. EMBO Rep, doi: 10.15252/embr.201949443 Link

Musheev MU, Baumgärtner A, Krebs L and Niehrs C (2020) The origin of genomic N6-methyl-deoxyadenosine in mammalian cells. Nat Chem Biol, doi: 10.1038/s41589-020-0504-2 Link

Niehrs C and Luke B (2020) Regulatory R-loops as facilitators of gene expression and genome stability. Nat Rev Mol Cell Biol, doi: 10.1038/s41580-019-0206-3 Link

Chang L-S, Kim M, Glinka A, Reinhard C and Niehrs C (2020) The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer. Elife, doi: 10.7554/eLife.51248 Link


Niehrs C and Calkhoven CF (2019) Emerging Role of C/EBPβ and Epigenetic DNA Methylation in Ageing. Trends Genet, doi: 10.1016/j.tig.2019.11.005 Link

Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A and Niehrs C (2019) NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. Elife, doi: 10.7554/eLife.49044 Link

Schüle KM, Leichsenring M, Andreani T, Vastolo V, Mallick M, Musheev MU, Karaulanov E and Niehrs C (2019) GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells.Genes Dev, doi: 10.1101/gad.325696.119 Link

Colditz J, Thiele S, Baschant U, Garbe AI, Niehrs C, Hofbauer LC and Rauner M (2019) Osteogenic Dkk1 Mediates Glucocorticoid-Induced but Not Arthritis-Induced Bone Loss. J Bone Miner Res, doi: 10.1002/jbmr.3702 Link

Aparisi Rey A, Karaulanov E, Sharopov S, Arab K, Schäfer A, Gierl M, Guggenhuber S, Brandes C, Pennella L, Gruhn WH, Jelinek R, Maul C, Conrad A, Kilb W, Luhmann HJ, Niehrs C and Lutz B (2019)  Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNA s . EMBO Rep, doi: 10.15252/embr.201846022 Link

Tsourdi E, Colditz J, Lademann F, Rijntjes E, Köhrle J, Niehrs C, Hofbauer LC and Rauner M (2019) The Role of Dickkopf-1 in Thyroid Hormone-Induced Changes of Bone Remodeling in Male Mice.Endocrinology, doi: 10.1210/en.2018-00998 Link

Arab K, Karaulanov E, Musheev M, Trnka P, Schäfer A, Grummt I and Niehrs C (2019) GADD45A binds R-loops and recruits TET1 to CpG island promoters. Nat Genet, doi: 10.1038/s41588-018-0306-6 Link