Publications since 2019


Nischwitz E, Schoonenberg VAC, Fradera-Sola A, Dejung M, Vydzhak O, Levin M, Luke B, Butter F and Scheibe M (2023) DNA damage repair proteins across the Tree of Life. iScience, doi: 10.1016/j.isci.2023.106778 Link

Schindler N, Tonn M, Kellner V, Fung JJ, Lockhart A, Vydzhak O, Juretschke T, Möckel S, Beli P, Khmelinskii A and Luke B (2022) Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase. Nat Commun, doi: 10.1038/s41467-023-36866-6 Link

Pires VB, Lohner N, Wagner T, Wagner CB, Wilkens M, Hajikazemi M, Paeschke K, Butter F and Luke B (2023) RNA-DNA hybrids prevent resection at dysfunctional telomeres. Cell Rep, doi: 10.1016/j.celrep.2023.112077 Link


Misino S, Busch A, Wagner CB and Luke B (2022) TERRA increases at short telomeres in yeast survivors and regulates survivor associated senescence (SAS). Nucleic Acids Res, doi: 10.1093/nar/gkac1125 Link

Wagner CB and Luke B (2022) DNA–RNA Hybrids at Telomeres in Budding Yeast. In: Aguilera, A., Ruzov, A. (eds) R-Loops . Methods in Molecular Biology, vol 2528. Humana, New York, NY,doi: 10.1007/978-1-0716-2477-7_10 Link

Kissling V, Reginato G, Bianco E, Kasaciunaite K, Tilma J, Cereghetti G, Lee SS, Guérois R, Seidel R, Cejka P and others (2021) Mre11-Rad50 oligomerization promotes DNA double-strand break repair. Nat Commun, doi: 10.1038/s41467-022-29841-0 Link

Guintini L, Paillé A, Graf M, Luke B, Wellinger RJ and Conconi A (2022) Transcription of ncRNAs promotes repair of UV induced DNA lesions in Saccharomyces cerevisiae subtelomeres. PLOS Genet, doi: 10.1371/journal.pgen.1010167 Link

Spada S, Luke B and Danckwardt S (2022) The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen. Front Genet, doi: 10.3389/fgene.2022.854907 Link

Pérez-Martínez L, Wagner T and Luke B (2022) Telomere Interacting Proteins and TERRA Regulation. Front Genet, doi: 10.3389/fgene.2022.872636 Link

Li L, Wang J, Yang Z, Zhao Y, Jiang H, Jiang L, Hou W, Ye R, He Q, Kupiec M, Luke B, Cao Q, Qi Z, Li Z and Lou H (2022) Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint. EMBO J, doi: 10.15252/embj.2021108290 Link


Mosler T, Conte F, Longo GMC, Mikicic I, Kreim N, Möckel MM, Petrosino G, Flach J, Barau J, Luke B, Roukos V and Beli P (2021) R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability. Nat Commun, doi: 10.1038/s41467-021-27530-y Link


Wagner T, Pérez-Martínez L, Schellhaas R, Barrientos-Moreno M, Öztürk M, Prado F, Butter F and Luke B (2020) Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence. PLOS Genet, doi: 10.1371/journal.pgen.1008603 Link

Vydzhak O, Bender K, Klermund J, Busch A, Reimann S and Luke B (2020) Checkpoint adaptation in recombination-deficient cells drives aneuploidy and resistance to genotoxic agents. DNA Repair (Amst), doi: 10.1016/j.dnarep.2020.102939 Link

Vydzhak O, Luke B and Schindler N (2020) Non-coding RNAs at the eukaryotic rDNA locus: RNA-DNA hybrids and beyond. J Mol Biol, doi: 10.1016/j.jmb.2020.05.011 Link

Pérez‐Martínez L, Öztürk M, Butter F and Luke B (2020) Npl3 stabilizes R‐loops at telomeres to prevent accelerated replicative senescence. EMBO Rep, doi: 10.15252/embr.201949087 Link

Niehrs C and Luke B (2020) Regulatory R-loops as facilitators of gene expression and genome stability. Nat Rev Mol Cell Biol, doi: 10.1038/s41580-019-0206-3 Link


Kellner V and Luke B (2019) Molecular and physiological consequences of faulty eukaryotic ribonucleotide excision repair. EMBO J, doi: 10.15252/embj.2019102309 Link

Lockhart A, Pires VB, Bento F, Kellner V, Luke-Glaser S, Yakoub G, Ulrich HD and Luke B (2019) RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids.Cell Rep, doi: 10.1016/j.celrep.2019.10.108 Link

Schmidt TT, Sharma S, Reyes GX, Kolodziejczak A, Wagner T, Luke B, Hofer A, Chabes A and Hombauer H (2019) Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio. Nucleic Acids Res, doi: 10.1093/nar/gkz1006 Link

Jolivet P, Serhal K, Graf M, Eberhard S, Xu Z, Luke B and Teixeira MT (2019) A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae.Sci Rep, doi: 10.1038/s41598-018-38000-9 Link