Publications since 2019

2021

Liebl MC and Hofmann TG (2021) The Role of p53 Signaling in Colorectal Cancer. Cancers (Basel), doi: 10.3390/cancers13092125 Link

Liebl MC, Moehlenbrink J, Becker H, Raddatz G, Abdeen SK, Aqeilan RI, Lyko F and Hofmann TG (2021) DAZAP2 acts as specifier of the p53 response to DNA damage. Nucleic Acids Res, doi: 10.1093/nar/gkab084 Link

2020

Allmann S, Mayer L, Olma J, Kaina B, Hofmann TG, Tomicic MT and Christmann M (2020) Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescence. Nucleic Acids Res, doi: 10.1093/nar/gkaa965 Link

Matos-Rodrigues GE, Grigaravicius P, Lopez BS, Hofmann T, Frappart P-O and Martins RAP (2020) ATRIP protects progenitor cells against DNA damage in vivo. Cell Death Dis, doi: 10.1038/s41419-020-03090-9 Link

Volcic M, Sparrer KMJ, Koepke L, Hotter D, Sauter D, Stürzel CM, Scherer M, Stamminger T, Hofmann TG, Arhel NJ, Wiesmüller L and Kirchhoff F (2020) Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1. Nat Microbiol, doi: 10.1038/s41564-020-0753-6 Link

Frappart P-O and Hofmann TG (2020) Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized Medicine. Cancers (Basel), doi: 10.3390/cancers12102750 Link

Matos-Rodrigues GE, Tan PB, Rocha-Martins M, Charlier CF, Gomes AL, Cabral-Miranda F, Grigaravicius P, Hofmann TG, Frappart P-O and Martins RAP (2020) Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of Atrip-Seckel syndrome. Dis Model Mech, doi: 10.1242/dmm.045807 Link

 

2019

Liebl MC and Hofmann TG (2019) Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road. BioEssays, doi: 10.1002/bies.201900127 Link

He Y, Roos WP, Wu Q, Hofmann TG and Kaina B (2019) The SIAH1–HIPK2–p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death.Mol Cancer Res, doi: 10.1158/1541-7786.MCR-18-1306 Link