Publications since 2019


Fischer MA, Mustafa AHM, Hausmann K, Ashry R, Kansy AG, Liebl MC, Brachetti C, Piée-Staffa A, Zessin M, Ibrahim HS, Hofmann TG, Schutkowski M, Sippl W and Krämer OH (2023) Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells. J Adv Res, doi: 10.1016/j.jare.2023.07.005 Link

Reuss DE, Downing SM, Camacho C V., Wang Y, Piro RM, Herold‐Mende C, Wang Z, Hofmann TG, Sahm F, von Deimling A, McKinnon PJ and Frappart P (2023) Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers High‐Grade Gliomas (HGG). Neuropathol Appl Neurobiol, doi: 10.1111/nan.12915 Link

Sigismondo G, Arseni L, Palacio-Escat N, Hofmann TG, Seiffert M and Krijgsveld J (2023) Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair. Nucleic Acids Res, 10.1093/nar/gkac1264 Link


Carlsson MJ, Vollmer AS, Demuth P, Heylmann D, Reich D, Quarz C, Rasenberger B, Nikolova T, Hofmann TG, Christmann M, Fuhlbrueck JA, Stegmüller S, Richling E, Cartus AT and Fahrer J (2022) p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol. Cell Death Dis, doi: 10.1038/s41419-022-05446-9 Link

Liebl MC and Hofmann TG (2022) Regulating the p53 Tumor Suppressor Network at PML Biomolecular Condensates. Cancers (Basel), doi: 10.3390/cancers14194549 Link

Hanisch D, Krumm A, Diehl T, Stork CM, Dejung M, Butter F, Kim E, Brenner W, Fritz G, Hofmann TG and Roos WP (2022) Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression. Cell Death Dis, doi:10.1038/s41419-022-04751-7 Link

Hill P, Zellmann F, Vukova T, Marini F, Kolmar S, Kaina B, Hofmann TG and Nikolova T (2022) Dose response to methylating agents in the γH2AX, SCE and colony formation assays: Effect of MGMT and MPG overexpression. Mutat Res - Genet Toxicol Environ Mutagen, doi: 10.1016/j.mrgentox.2022.503462 Link

Clemm von Hohenberg K, Müller S, Schleich S, Meister M, Bohlen J, Hofmann TG and Teleman AA (2022) Cyclin B/CDK1 and Cyclin A/CDK2 phosphorylate DENR to promote mitotic protein translation and faithful cell division. Nat Commun, doi: 10.1038/s41467-022-28265-0 Link


Formes H, Bernardes JP, Mann A, Bayer F, Pontarollo G, Kiouptsi K, Schäfer K, Attig S, Nikolova T, Hofmann TG, Schattenberg JM, Todorov H, Gerber S, Rosenstiel P, Bopp T, Sommer F and Reinhardt C (2021) The gut microbiota instructs the hepatic endothelial cell transcriptome. iScience, doi: 10.1016/j.isci.2021.103092 Link

Dietrich C and Hofmann TG (2021) Ferroptosis Meets Cell–Cell Contacts. Cells, doi: 10.3390/cells10092462 Link

Liebl MC and Hofmann TG (2021) The Role of p53 Signaling in Colorectal Cancer. Cancers (Basel), doi: 10.3390/cancers13092125 Link

Liebl MC, Moehlenbrink J, Becker H, Raddatz G, Abdeen SK, Aqeilan RI, Lyko F and Hofmann TG (2021) DAZAP2 acts as specifier of the p53 response to DNA damage. Nucleic Acids Res, doi: 10.1093/nar/gkab084 Link


Allmann S, Mayer L, Olma J, Kaina B, Hofmann TG, Tomicic MT and Christmann M (2020) Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescence. Nucleic Acids Res, doi: 10.1093/nar/gkaa965 Link

Matos-Rodrigues GE, Grigaravicius P, Lopez BS, Hofmann T, Frappart P-O and Martins RAP (2020) ATRIP protects progenitor cells against DNA damage in vivo. Cell Death Dis, doi: 10.1038/s41419-020-03090-9 Link

Volcic M, Sparrer KMJ, Koepke L, Hotter D, Sauter D, Stürzel CM, Scherer M, Stamminger T, Hofmann TG, Arhel NJ, Wiesmüller L and Kirchhoff F (2020) Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1. Nat Microbiol, doi: 10.1038/s41564-020-0753-6 Link

Frappart P-O and Hofmann TG (2020) Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized Medicine. Cancers (Basel), doi: 10.3390/cancers12102750 Link

Matos-Rodrigues GE, Tan PB, Rocha-Martins M, Charlier CF, Gomes AL, Cabral-Miranda F, Grigaravicius P, Hofmann TG, Frappart P-O and Martins RAP (2020) Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of Atrip-Seckel syndrome. Dis Model Mech, doi: 10.1242/dmm.045807 Link



Liebl MC and Hofmann TG (2019) Identification of responders to immune checkpoint therapy: which biomarkers have the highest value?J Eur Acad Dermatology Venereol, doi: 10.1111/jdv.15992 Link

Liebl MC and Hofmann TG (2019) Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road. BioEssays, doi: 10.1002/bies.201900127 Link

He Y, Roos WP, Wu Q, Hofmann TG and Kaina B (2019) The SIAH1–HIPK2–p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death.Mol Cancer Res, doi: 10.1158/1541-7786.MCR-18-1306 Link