Publications since 2019

2021

Schwarzenbach C, Tatsch L, Brandstetter Vilar J, Rasenberger B, Beltzig L, Kaina B, Tomicic MT and Christmann M (2021) Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment. Cancers (Basel), doi: 10.3390/cancers13143585 Link

Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti, Schäberle TF, Plubrukarn A and Fahrer J (2021) Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer. Cancers (Basel), doi: 10.3390/cancers13133282 Link

Kostka T, Empl MT, Seiwert N, Geisen SM, Hoffmann P, Adam J, Seeger B, Shay JW, Christmann M, Sturla SJ, Fahrer J and Steinberg P (2021) Repair of O 6-carboxymethylguanine adducts by O 6-methylguanine-DNA methyltransferase in human colon epithelial cells. Carcinogenesis, doi: 10.1093/carcin/bgab049 Link

Reich TR, Schwarzenbach C, Vilar JB, Unger S, Mühlhäusler F, Nikolova T, Poplawski A, Baymaz HI, Beli P, Christmann M and Tomicic MT (2021) Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination. Cell Mol Life Sci, doi: 10.1007/s00018-021-03864-0 Link

Tomicic MT, Krämer F, Nguyen A, Schwarzenbach C and Christmann M (2021) Oxaliplatin-induced senescence in colorectal cancer cells depends on P14ARF-mediated sustained p53 activation. Cancers (Basel), doi: 10.3390/cancers13092019 Link

2019

Tomicic MT, Steigerwald C, Rasenberger B, Brozovic A and Christmann M (2019) Functional mismatch repair and inactive p53 drive sensitization of colorectal cancer cells to irinotecan via the IAP antagonist BV6. Arch Toxicol, doi: 10.1007/s00204-019-02513-7 Link

Neitzel C, Seiwert N, Göder A, Diehl E, Weber C, Nagel G, Stroh S, Rasenberger B, Christmann M and Fahrer J (2019) Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation. Cells, doi: 10.3390/cells8080794 Link

Kaina B and Christmann M (2019) DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas.DNA Repair (Amst), doi: 10.1016/j.dnarep.2019.04.007 Link

Aasland D, Gotzinger L, Hauck L, Berte N, Meyer J, Effenberger M, Schneider S, Reuber EE, Roos WP, Tomicic MT, Kaina B and Christmann M (2019) Temozolomide induces senescence and repression of DNA repair pathways in glioblastoma cells via activation of ATR–Chk1, p21, and NF-kB. Cancer Res, doi: 10.1158/0008-5472.CAN-18-1733 Link