Publications 2019-2022


Penner I, Büscher N, Dejung M, Freiwald A, Butter F and Plachter B (2022) Subviral Dense Bodies of Human Cytomegalovirus Induce an Antiviral Type I Interferon Response. Cells, doi: 10.3390/cells11244028 Link

Trindade S, Niz M De, Sequeira M, Bizarra-Rebelo T, Bento F, Dejung M, Ferreira J, Butter F, Bringaud F, Gjini E and Figueiredo L (2022) Persistence behavior in African trypanosomes during adipose tissue colonization. Nat Portf, doi: 10.1038/s41467-022-34622-w Link

Öztürk M, Freiwald A, Cartano J, Schmitt R, Dejung M, Luck K, Al-Sady B, Braun S, Levin M and Butter F (2022) Proteome effects of genome-wide single gene perturbations.Nat Commun, doi: 10.1038/s41467-022-33814-8 Link

Schmidt H, Mauer K, Glaser M, Dezfuli BS, Hellmann SL, Silva Gomes AL, Butter F, Wade RC, Hankeln T and Herlyn H (2022) Identification of antiparasitic drug targets using a multi-omics workflow in the acanthocephalan model. BMC Genomics, doi: 10.1186/s12864-022-08882-1 Link

Krauter S, Büscher N, Bräuchle E, Ortega Iannazzo S, Penner I, Krämer N, Gogesch P, Thomas S, Kreutz M, Dejung M, Freiwald A, Butter F, Waibler Z and Plachter B (2022) An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine. Vaccines, doi: 10.3390/vaccines10081326 Link

Levin M and Butter F (2022) Proteotranscriptomics – A facilitator in omics research. Comput Struct Biotechnol J, doi: 10.1016/j.csbj.2022.07.007 Link

Vellmer T, Hartleb L, Fradera Sola A, Kramer S, Meyer-Natus E, Butter F and Janzen CJ (2022) A novel SNF2 ATPase complex in Trypanosoma brucei with a role in H2A.Z-mediated chromatin remodelling. PLOS Pathog, doi: 10.1371/journal.ppat.1010514 Link

Marnik EA, Almeida M V., Cipriani PG, Chung G, Caspani E, Karaulanov E, Butter F, Sharp CS, Zinno J, Gan HH, Piano F, Ketting RF, Gunsalus KC and Updike DL (2021) The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline. PLOS Genet, doi: 10.1371/journal.pgen.1010245 Link

Hanisch D, Krumm A, Diehl T, Stork CM, Dejung M, Butter F, Kim E, Brenner W, Fritz G, Hofmann TG and Roos WP (2022) Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression. Cell Death Dis, doi:10.1038/s41419-022-04751-7 Link

Schreier J, Dietz S, Boermel M, Oorschot V, Seistrup A-S, de Jesus Domingues AM, Bronkhorst AW, Nguyen DAH, Phillis S, Gleason EJ, L’Hernault SW, Phillips CM, Butter F and Ketting RF (2022) Membrane-associated cytoplasmic granules carrying the Argonaute protein WAGO-3 enable paternal epigenetic inheritance in Caenorhabditis elegans. Nat Cell Biol, doi: 10.1038/s41556-021-00827-2 Link


Eisenhuth N, Vellmer T, Rauh ET, Butter F and Janzen CJ (2021) A DOT1B/Ribonuclease H2 Protein Complex Is Involved in R-Loop Processing, Genomic Integrity, and Antigenic Variation in Trypanosoma brucei. MBio, doi: 10.1128/mBio.01352-21 Link

Dallaire A, Manley BF, Wilkens M, Bista I, Quan C, Evangelisti E, Bradshaw CR, Ramakrishna NB, Schornack S, Butter F, Paszkowski U and Miska EA (2021) Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis. Genome Res, doi: 10.1101/gr.275752.121 Link

Bakari-Soale M, Ikenga NJ, Scheibe M, Butter F, Jones NG, Kramer S and Engstler M (2021) The nucleolar DExD/H protein Hel66 is involved in ribosome biogenesis in Trypanosoma brucei. Sci Rep, doi: 10.1038/s41598-021-97020-0 Link

Deen D, Butter F, Daniels DE, Ferrer-Vicens I, Ferguson DCJ, Holland ML, Samara V, Sloane-Stanley JA, Ayyub H, Mann M, Frayne J, Garrick D and Vernimmen D (2021) Identification of the transcription factor MAZ as a regulator of erythropoiesis. Blood Adv, doi: 10.1182/bloodadvances.2021004609 Link

Pons M, Zeyn Y, Zahn S, Mahendrarajah N, Page BDG, Gunning PT, Moriggl R, Brenner W, Butter F and Krämer OH (2021) Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis Inhibition. Cancers (Basel), doi: 10.3390/cancers13143464 Link

Dietz S, Almeida MV, Nischwitz E, Schreier J, Viceconte N, Fradera-Sola A, Renz C, Ceron-Noriega A, Ulrich HD, Kappei D, Ketting RF and Butter F (2021) The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1. Nat Commun, doi: 10.1038/s41467-021-22861-2 Link

Maynard D, Viehhauser A, Knieper M, Dreyer A, Manea G, Telman W, Butter F, Chibani K, Scheibe R and Dietz KJ (2021) The in vitro interaction of 12‐oxophytodienoic acid and related conjugated carbonyl compounds with thiol antioxidants. Biomolecules, doi: 10.3390/biom11030457 Link

Davies C, Ooi C-P, Sioutas G, Hall BS, Sidhu H, Butter F, Alsford S, Wickstead B and Rudenko G (2021) TbSAP is a novel chromatin protein repressing metacyclic variant surface glycoprotein expression sites in bloodstream form Trypanosoma brucei . Nucleic Acids Res, doi: 10.1093/nar/gkab109 Link

Berkyurek AC, Furlan G, Lampersberger L, Beltran T, Weick E, Nischwitz E, Cunha Navarro I, Braukmann F, Akay A, Price J, Butter F, Sarkies P and Miska EA (2021) The RNA polymerase II subunit RPB‐9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription. EMBO J, doi: 10.15252/embj.2020105565 Link

Amodeo S, Kalichava A, Fradera-Sola A, Bertiaux-Lequoy E, Guichard P, Butter F and Ochsenreiter T (2021) Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei. J Cell Sci, doi: 10.1242/jcs.254300 Link

Stoldt M, Klein L, Beros S, Butter F, Jongepier E, Feldmeyer B and Foitzik S (2021) Parasite Presence Induces Gene Expression Changes in an Ant Host Related to Immunity and Longevity. Genes (Basel), doi: 10.3390/genes12010095 Link

Worpenberg L, Paolantoni C, Longhi S, Mulorz MM, Lence T, Wessels H, Dassi E, Aiello G, Sutandy FXR, Scheibe M, Edupuganti RR, Busch A, Möckel MM, Vermeulen M, Butter F, König J, Notarangelo M, Ohler U, Dieterich C, Quattrone A, Soldano A and Roignant J (2021) Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila. EMBO J, doi: 10.15252/embj.2020104975 Link


Wagner T, Pérez-Martínez L, Schellhaas R, Barrientos-Moreno M, Öztürk M, Prado F, Butter F and Luke B (2020) Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence. PLOS Genet, doi: 10.1371/journal.pgen.1008603 Link

Placentino M, Jesus Domingues AM, Schreier J, Dietz S, Hellmann S, Albuquerque BF, Butter F and Ketting RF (2020) Intrinsically disordered protein PID‐2 modulates Z granules and is required for heritable piRNA‐induced silencing in the Caenorhabditis elegans embryo. EMBO J, doi: 10.15252/embj.2020105280 Link

Greither T, Schumacher J, Dejung M, Behre HM, Zischler H, Butter F and Herlyn H (2020) Fertility Relevance Probability Analysis Shortlists Genetic Markers for Male Fertility Impairment. Cytogenet Genome Res, doi: 10.1159/000511117 Link

Viceconte N, Loriot A, Lona Abreu P, Scheibe M, Fradera Sola A, Butter F, De Smet C, Azzalin CM, Arnoult N and Decottignies A (2020) PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells. RNA, doi: 10.1261/rna.076281.120 Link

Levin M, Scheibe M and Butter F (2020) Proteotranscriptomics assisted gene annotation and spatial proteomics of Bombyx mori BmN4 cell line. BMC Genomics, doi: 10.1186/s12864-020-07088-7 Link

Leal AZ, Schwebs M, Briggs E, Weisert N, Reis H, Lemgruber L, Luko K, Wilkes J, Butter F, McCulloch R and Janzen CJ (2020) Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation. Nucleic Acids Res, doi: 10.1093/nar/gkaa686 Link

Bruch A, Laguna T, Butter F, Schaffrath R and Klassen R (2020) Misactivation of multiple starvation responses in yeast by loss of tRNA modifications. Nucleic Acids Res, doi: 10.1093/nar/gkaa455 Link

Casas-Vila N, Sayols S, Pérez-Martínez L, Scheibe M and Butter F (2020) The RNA fold interactome of evolutionary conserved RNA structures in S. cerevisiae.Nat Commun, doi: 10.1038/s41467-020-16555-4 Link

Dolezelová E, Kunzová M, Dejung M, Levin M, Panicucci B, Regnault C, Janzen CJ, Barrett MP, Butter F and Zíková A (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLOS Biol, doi: 10.1371/journal.pbio.3000741 Link

Pérez‐Martínez L, Öztürk M, Butter F and Luke B (2020) Npl3 stabilizes R‐loops at telomeres to prevent accelerated replicative senescence. EMBO Rep, doi: 10.15252/embr.201949087 Link

Scherer M, Levin M, Butter F and Scheibe M (2020) Quantitative Proteomics to Identify Nuclear RNA-Binding Proteins of Malat1. Int J Mol Sci, doi: 10.3390/ijms21031166 Link

Zimmermann C, Krämer N, Krauter S, Strand D, Sehn E, Wolfrum U, Freiwald A, Butter F and Plachter B (2020) Autophagy interferes with human cytomegalovirus genome replication, morphogenesis, and progeny release. Autophagy, doi: 10.1080/15548627.2020.1732686 Link

Kiweler N, Wünsch D, Wirth M, Mahendrarajah N, Schneider G, Stauber RH, Brenner W, Butter F and Krämer OH (2020) Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes. J Cancer Res Clin Oncol, doi: 10.1007/s00432-019-03118-4 Link


Warncke JD, Passecker A, Kipfer E, Brand F, Pérez-Martínez L, Proellochs NI, Kooij TWA, Butter F, Voss TS and Beck H (2019) The PHIST Protein GEXP02 Targets the Host Cytoskeleton During Sexual Development of Plasmodium falciparum.Cell Microbiol, doi: 10.1111/cmi.13123 Link

Goos C, Dejung M, Wehman AM, M-Natus E, Schmidt J, Sunter J, Engstler M, Butter F and Kramer S (2019) Trypanosomes can initiate nuclear export co-transcriptionally.Nucleic Acids Res, doi: 10.1093/nar/gky1136 Link

Cordeiro Rodrigues RJ, de Jesus Domingues AM, Hellmann S, Dietz S, de Albuquerque BFM, Renz C, Ulrich HD, Sarkies P, Butter F and Ketting RF (2019) PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability.Genes Dev, doi: 10.1101/gad.322446.118 Link

Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW and Ramming A (2019) PU.1 controls fibroblast polarization and tissue fibrosis.Nature, doi: 10.1038/s41586-019-0896-x Link

Bluhm A, Viceconte N, Li F, Rane G, Ritz S, Wang S, Levin M, Shi Y, Kappei D and Butter F (2019) ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.Nucleic Acids Res,doi: 10.1093/nar/gky1289 Link