New publications from the Ulrich lab - Analysing DNA single-strand breaks


The Ulrich lab has published a detailed protocol for GLOE-Seq, their new method for genome-wide mapping of these lesions, in STAR Protocols:

Moreover, Nicola Zilio & Helle Ulrich review classical & new high-resolution NGS approaches for genome-wide mapping in The FEBS Journal:

Petrosino G, Zilio N, Sriramachandran AM and Ulrich HD (2020) Preparation and analysis of GLOE-Seq libraries for genome-wide mapping of DNA replication patterns, single-strand breaks, and lesions.  STAR Protocols, doi: 10.1016/j.xpro.2020.100076

Zilio N & Ulrich HD (2020) Exploring the SSBreakome: genome‐wide mapping of DNA single‐strand breaks by next‐generation sequencing. The FEBS Journal, doi: 10.1111/febs.15568