Dikic

2020

van der Heden van Noort G, Madern JM, Kim RQ, Misra M, Dikic I, Zhang Y, Ovaa H, Codee JDC and Filippov D V. (2020) Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitinating Enzyme SdeC. ChemBioChem, cbic.202000230 Link

Putyrski M, Vakhrusheva O, Bonn F, Guntur S, Vorobyov A, Brandts C, Dikic I and Ernst A (2020) Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine. Front Cell Dev Biol, doi: 10.3389/fcell.2020.00208 Link

Tiku V, Tan M-W and Dikic I (2020) Mitochondrial Functions in Infection and Immunity. Trends Cell Biol, 30:263–275 Link

Maddi K, Sam DK, Bonn F, Prgomet S, Tulowetzke E, Akutsu M, Lopez-Mosqueda J and Dikic I (2020) Wss1 Promotes Replication Stress Tolerance by Degrading Histones. Cell Rep, 30:3117-3126.e4 Link

Hübner CA and Dikic I (2020) ER-phagy and human diseases. Cell Death Differ, 27:833–842 Link

Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, Widera D, Fulda S, Wajant H, van Wijk SJL, Dikic I and Heilemann M (2020) Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells. Sci Signal, 13:eaax5647 Link

2019

Pohl C and Dikic I (2019) Cellular quality control by the ubiquitin-proteasome system and autophagy. Science (80- ), 366:818–822 Link

Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G and Dikic I (2019) TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease.EMBO Rep, e48317

Shin D, Mukherjee R, Liu Y, Gonzalez A, Bonn F, Liu Y, Rogov V V., Heinz M, Stolz A, Hummer G, Dötsch V, Luo Z-Q, Bhogaraju S and Dikic I (2019) Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB. Mol Cell, doi: 10.1016/j.molcel.2019.10.019 Link

Bhogaraju S, Bonn F, Mukherjee R, Adams M, Pfleiderer MM, Galej WP, Matkovic V, Lopez-Mosqueda J, Kalayil S, Shin D and Dikic I (2019) Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation. Nature, doi: 10.1038/s41586-019-1440-8Link

Forrester A, De Leonibus C, Grumati P, Fasana E, Piemontese M, Staiano L, Fregno I, Raimondi A, Marazza A, Bruno G, Iavazzo M, Intartaglia D, Seczynska M, van Anken E, Conte I, De Matteis MA, Dikic I, Molinari M and Settembre C (2019) A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex. EMBO J, 38:e99847 Link

Huber J, Obata M, Gruber J, Akutsu M, Löhr F, Rogova N, Güntert P, Dikic I, Kirkin V, Komatsu M, Dötsch V and Rogov V V. (2019) An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 1–15 Link

Linder B, Wehle A, Hehlgans S, Bonn F, Dikic I, Rödel F, Seifert V and Kögel D (2019) Arsenic Trioxide and (−)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling. Cancers (Basel), 11:350 Link

Tiku V and Dikic I (2019) Autophagy without conjugation. Nat Struct Mol Biol, 26:249–250 Link

Poluzzi C, Nastase MV, Zeng-Brouwers J, Roedig H, Hsieh LTH, Michaelis JB, Buhl EM, Rezende F, Manavski Y, Bleich A, Boor P, Brandes RP, Pfeilschifter J, Stelzer EHK, Münch C, Dikic I, Brandts C, Iozzo R V., Wygrecka M and Schaefer L (2019) Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury. Kidney Int, 95:540–562 Link

Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, Hebel M, Hayes MG, Schaubeck S, Benner C, Heinz S, Bremm A, Dikic I, Ernst A and Kaulich M (2019) Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. Elife, doi: 10.7554/eLife.42549 Link

Bhaskara RM, Grumati P, Garcia-Pardo J, Kalayil S, Covarrubias-Pinto A, Chen W, Kudryashev M, Dikic I and Hummer G (2019) Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy. Nat Commun, 10:2370 Link

Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I and Potente M (2019) Deubiquitinase USP10 regulates notch signaling in the endothelium. Science (80- ), 364:188–193 Link

Nguyen D, Shaid S, Vakhrusheva O, Koschade SE, Klann K, Thölken M, Baker F, Zhang J, Oellerich T, Sürün D, Derlet A, Haberbosch I, Eimer S, Osiewacz HD, Behrends C, Münch C, Dikic I and Brandts CH (2019) Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy. Blood, 133:168–179 Link

Herhaus L, van den Bedem H, Tang S, Maslennikov I, Wakatsuki S, Dikic I and Rahighi S (2019) Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains. J Mol Biol, doi: 10.1016/j.jmb.2019.06.012 Link

Mukherjee R and Dikic I (2019) NIPSNAP Beacons in Mitophagy. Dev Cell, 49:503–505 Link

Juretschke T, Beli P and Dikic I (2019) Quantitative phosphoproteomics of selective autophagy receptors. Pages 691–701 in: Methods in Molecular Biology, vol. 1880 Link

van Wijk SJ, Fulda S, Dikic I and Heilemann M (2019) Visualizing ubiquitination in mammalian cells. EMBO Rep, 20:e46520 Link